Searchable abstracts of presentations at key conferences in endocrinology

ea0037gp.29.06 | Endocrine tumours and neoplasia – Adrenal Tumour | ECE2015

The incidence of consecutive manifestations of VHL disease

Frantzen Carlijn , Kruizinga Roeliene C , Sluiter Wim J , de Vries Elisabeth G E , Zonnenberg Bernard A , Lips Cornelis J , Walenkamp Annemiek M E , van der Horst-Schrivers Anouk N A , Links Thera P

Background: Von Hippel Lindau (VHL) disease is a rare tumour syndrome with a high penetrance. VHL mutation carriers develop numerous disease related manifestations in multiple organs during life, but precise difference in growth velocity and incidence of lesions in different organs is still unknown. We aimed to gain insight in the incidence of consecutive new disease manifestations in the organs of patients with VHL.Patients and methods: Clinical data in...

ea0026p66 | Endocrine tumours and neoplasia | ECE2011

Metabolic endocrine tumor activity is reflected by total 18F-DOPA PET tumor uptake in patients with a carcinoid tumor

Fiebrich H-B , de Jong J R , Kema I P , Koopmans K P , Sluiter W J , Dierckx R A J O , Walenkamp A M E , Brouwers A H , de Vries E G E , Links T P

Introduction: Positron emission tomography (PET) using 6-[F-18]fluoro-L-dihydroxyphenylalanine (18F-DOPA) has an excellent sensitivity to detect carcinoid tumor lesions. 18F-DOPA-tumor uptake and the levels of biochemical tumor markers are mediated by tumor endocrine metabolic activity. Therefore we evaluated whether total 18F-DOPA-tumor uptake on PET, defined as the whole-body metabolic burden (WBMTB) reflects tumor load per pat...